Gut microbiota–bile acid–interleukin-22 axis orchestrates polycystic ovary syndrome
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چکیده
منابع مشابه
Role of Gut Microbiome in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 8-13% of women at reproductive age worldwide. This disorder is usually associated with menstrual disorders, infertility, obesity, and insulin resistance. The underlying cause of this syndrome is unknown, however in recent years, researchers have shown an association between intestinal microbiota alterations )dysbiosi...
متن کاملPolycystic ovary syndrome. Polycystic ovary syndrome.
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متن کاملUNILATERAL POLYCYSTIC OVARY SYNDROME
Two-hundred and seventeen subjects underwent transvaginal ultrasound -17 (8%) had unilateral polycystic ovary (PCO). Twelve percent of subjects with unilateral scan-pea had oligomenorrhea, 24% were amenorrheic, 23% were hirsute and 29% had acne. Biochemical parameters were compared between subjects with unilateral scan- PCO and those with bilateral scan- PCO (n=200) as well as a group of s...
متن کاملAssociation between Polycystic Ovary Syndrome and Gut Microbiota
Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in women of reproductive age. It is difficult to treat PCOS because of its complex etiology and pathogenesis. Here, we characterized the roles of gut microbiota on the pathogenesis and treatments in letrozole (a nonsteroidal aromatase inhibitor) induced PCOS rat model. Changes in estrous cycles, hormonal levels, ovarian morpho...
متن کاملTreating Polycystic Ovary Syndrome with TCM Polycystic Ovary Syndrome (PCOS)
Women are usually diagnosed when in their 20s or 30s, but PCOS may also affect teenage girls. The symptoms often begin when a girl's periods start. Women with this disorder often have a mother or sister who has symptoms similar to those of PCOS. The main features are obesity, anovulation or amenorrhea, acne, and excessive hair growth. It is thought to be one of the leading causes of female infe...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 2019
ISSN: 1078-8956,1546-170X
DOI: 10.1038/s41591-019-0509-0